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M9480578.TXT
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1994-08-20
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Document 0578
DOCN M9480578
TI CT of primary colonic lymphoma.
DT 9410
AU Wyatt SH; Fishman EK; Hruban RH; Siegelman SS; Russell H. Morgan
Department of Radiology and Radiological; Science, Johns Hopkins Medical
Institutions, Baltimore, Maryland.
SO Clin Imaging. 1994 Apr-Jun;18(2):131-41. Unique Identifier : AIDSLINE
MED/94306283
AB The article presents the computed tomography (CT) findings in 15
patients with histopathologically proven primary lymphoma of the
colorectum. CT is invaluable for the characterization of primary colonic
lymphomas and for definition of tumor invasion and spread. The lymphomas
in our series were categorized according to their CT appearance as
either discrete bulky masses (n = 6), focal mural infiltration (n = 5),
or diffuse colonic invasion (n = 5). Primary colonic lymphomas that were
manifested as mass lesions had a greater depth of mural invasion (x =
4.3 cm) than did infiltrative lesions (x = 2.7 cm, P < .05), and tended
to present at an earlier stage. In the setting of solitary mass lesions
in the colon that are not associated with adenopathy, CT findings can
help to distinguish primary lymphoma from adenocarcinoma. Cecal tumors
that grow into the terminal ileum, tumors which are fairly well
demarcated from the surrounding pericolonic fat and show no evidence of
invasion or obstruction of neighboring viscera, and tumors which
perforate in the absence of desmoplastic reaction should suggest
lymphoma. A clinical history of human immunodeficiency virus infection
should also prompt consideration of colonic lymphoma.
DE Adenocarcinoma/PATHOLOGY/RADIOGRAPHY Adult Aged Colonic
Neoplasms/PATHOLOGY/*RADIOGRAPHY Diagnosis, Differential Female Human
Lymphoma/PATHOLOGY/*RADIOGRAPHY Lymphoma,
AIDS-Related/PATHOLOGY/RADIOGRAPHY Male Middle Age Neoplasm
Invasiveness Rectal Neoplasms/PATHOLOGY/*RADIOGRAPHY *Tomography,
X-Ray Computed JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).